Doctor Discussion Guide

You probably have lots of questions about your treatment and finding an appropriate choice for moving forward with your treatment plan, so we created this Doctor Discussion Guide to help you get your questions organized for your next doctor's visit.

Your doctor will likely be conducting an A1C test to measure your average blood sugar control for the past 2 to 3 months. The results from your A1C test will show how well you are currently managing your type 2 diabetes. If your A1C level continues to be too high, you and your doctor may decide it's time to add another oral medication to your treatment. TRADJENTA is an option you and your doctor may decide is right for you.

TRADJENTA is a prescription medicine that is used along with diet and exercise to help lower A1C levels in adults with type 2 diabetes. TRADJENTA works to regulate blood sugar, especially after meals, when sugar levels rise. As with any treatment plan, you should discuss your options thoroughly with your doctor.

TRADJENTA is not for people with type 1 diabetes or for people with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had inflammation of the pancreas (pancreatitis) in the past, it is not known if you have a higher chance of getting pancreatitis while you take TRADJENTA.

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    What is TRADJENTA?

    TRADJENTA is a prescription medicine that is used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

    TRADJENTA is not for people with type 1 diabetes or for people with diabetic ketoacidosis (increased ketones in the blood or urine).

    If you have had inflammation of the pancreas (pancreatitis) in the past, it is not known if you have a higher chance of getting pancreatitis while you take TRADJENTA.

    IMPORTANT SAFETY INFORMATION

    What is the most important information I should know about TRADJENTA?

    Serious side effects can happen to people taking TRADJENTA, including inflammation of the pancreas (pancreatitis), which may be severe and lead to death. Before you start taking TRADJENTA, tell your doctor if you have ever had pancreatitis, gallstones, a history of alcoholism, or high triglyceride levels.

    Stop taking TRADJENTA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

    Who should not take TRADJENTA?

    Do not take TRADJENTA if you are allergic to linagliptin or any of the ingredients in TRADJENTA.

    Symptoms of a serious allergic reaction to TRADJENTA may include rash, itching, flaking or peeling; raised red patches on your skin (hives); swelling of your face, lips, tongue and throat that may cause difficulty breathing or swallowing. If you have any symptoms of a serious allergic reaction, stop taking TRADJENTA and call your doctor or go to the emergency room right away.

    What should I tell my doctor before using TRADJENTA?

    Tell your doctor about all your medical conditions, including if you have or have had inflammation of your pancreas (pancreatitis).

    Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. TRADJENTA may affect the way other medicines work, and other medicines may affect how TRADJENTA works. Especially tell your doctor if you take

    • other medicines that can lower your blood sugar. If you take TRADJENTA with another medicine that can cause low blood sugar, such as sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea or insulin may need to be lowered while you take TRADJENTA.
    • rifampin (Rifadin®, Rimactane®, Rifater®, Rifamate®)*, an antibiotic that is used to treat tuberculosis.

    Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding or plan to breastfeed.

    What are the possible side effects of TRADJENTA?

    TRADJENTA may cause serious side effects, including

    • Inflammation of the pancreas (pancreatitis).
    • Low blood sugar (hypoglycemia), especially if you take TRADJENTA with another medicine that can cause low blood sugar. Signs and symptoms of low blood sugar may include headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, or feeling jittery.
    • Allergic (hypersensitivity) reactions can happen after your first dose or up to 3 months after starting TRADJENTA. Symptoms may include swelling of your face, lips, throat, and other areas on your skin; difficulty with swallowing or breathing; raised, red areas on your skin (hives); skin rash, itching, flaking, or peeling.

    The most common side effects of TRADJENTA include stuffy or runny nose, sore throat, cough and diarrhea.

    These are not all the possible side effects of TRADJENTA. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

    TJ CONS ISI 28MAY2014

    For more safety information, please see Medication Guide and full Prescribing Information.

    *The brands listed are trademarks of their respective owners and are not trademarks of Boehringer Ingelheim Pharmaceuticals, Inc. The makers of these brands are not affiliated with and do not endorse Boehringer Ingelheim Pharmaceuticals, Inc., or its products.